Science-Driven Efficacy

We offer in vivo pharmacology services to Pharmaceutical, Biotech and Agrofood companies to assess the efficacy and mechanisms of action of health products addressing Metabolic Diseases, GI Disorders and Muscle-Wasting Conditions.

We offer tailor-made preclinical in vivo efficacy studies.

With over 80 years of cumulative experience, knowledge and skills in the study of Metabolic diseases, GI disorders and Muscle-wasting conditions, we excel in the development of relevant disease models and the mastery of gold-standard methods that both ensure accurate, reliable and high-added value data.

Our expertise

Metabolic diseases

Metabolic diseases, such as obesity, diabetes, dyslipidemia, or NAFL/NASH, affect millions of people worldwide and can severely affect their quality of life. While treatments have improved for many of these diseases, a high need of developed, safe, and effective therapeutics remains. Thanks to our strong expertise in metabolic diseases and their complications as well as in the preclinical evaluation of your compound, BIOMEOSTASIS can help you in your development process. 

Obesity

Excess body fat impacting health Learn more

MASLD/MASH

Metabolic Dysfunction-associated liver diseases Learn more

Atherosclerosis

Artery blockage leading to heart disease Learn more

Diabetes

Disruption of insulin action & glucose homeostasis Learn more

Binge eating

The most common eating disorder worldwide Learn more

GI disorders

 GI disorders include conditions such as constipation, diarrhea, and inflammatory bowel diseases (Crohn’s disease, ulcerative colitis…). At BIOMEOSTASIS, based on our expertise in these therapeutic areas, we developed specific rodent models of such disorders that constitutes powerful tools for the preclinical assessment of your compounds. 

CONSTIPATION

A chronic condition that negatively impacts quality of life Learn more

IBD

Inflammatory conditions of the GI track Learn more

Muscle-wasting

Muscle wasting is a debilitating condition that develops with ageing as a physiological response to fasting or malnutrition, and in many diseases, including cancer-associated cachexia, sarcopenia diabetes, or cardiac failure. The loss of muscle mass or strength primarily results from excessive protein breakdown and reduced protein synthesis. Genetic diseases such as in the Duchenne muscular Dystrophy can also lead to muscular dysfunction. The loss of muscle function can lead to reduced quality of life, increased morbidity and mortality.

SARCOPENIA

Age-related muscle loss Learn more

DMD

Genetic disorder causing muscle degeneration Learn more

CACHEXIA

Severe muscle wasting and weight loss conditionLearn more

We help you optimize and anticipate the success of your health products.

From screening to chronic treatment studies, our established rodent models and experimental paradigms allow you to obtain high-added value data on the efficacy and mechanisms of action of your health products in order to optimize and anticipate their clinical success.

As we like to say at BIOMEOSTASIS,

in vivo VERITAS !”

Founded in 2010 by Bruno BARIOHAY, Ph.D. and Julien ROUX, Ph.D., Biomeostasis has been implicated in more than three hundred and fifty in vivo preclinical projects to date. The company endeavors to put its corporate values, i.e., Quality, Ethics and Flexibility, at the heart of each project. While these values are now well recognized worldwide, the company is proud to display a near 100% customer satisfaction rate. This recognition is a result of our passion, our listening to customers and of an expert scientific team dedicated to each of the projects conducted at Biomeostasis.

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